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Predisposition for breast cancer risk

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A core needle biopsy uses a long, hollow tube to extract a sample of tissue. Here, a biopsy of a suspicious breast lump is being done. The sample is sent to a laboratory for testing. During a breast MRI , you lie on your stomach on a padded scanning table. Your breasts fit into a hollow depression in the table, which contains coils that detect magnetic signals. The table slides into the large opening of the MRI machine.
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The Breast Cancer Risk Assessment Tool

Predisposition for breast cancer risk
Predisposition for breast cancer risk
Predisposition for breast cancer risk
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Breast Cancer Risk Assessment Tool

This image is an example of the kind of gel pictures researchers use to understand the order, or sequence, of genes or to look for mutations in genes. Out of people with breast cancer about 15 will have triple-negative breast cancer TNBC. If doctors had a way to identify women at risk for TNBC, they might be able to find cancer earlier and before it spreads when it might be easier to treat. One approach researchers are using to identify women at risk for TNBC and possible treatment options for TNBC is by studying inherited changes mutations in cancer genes. These genes are known by several names: breast-cancer-risk genes, cancer-predisposition genes, and cancer-susceptibility genes. Couch and his research team used a technology called multigene panel testing on blood samples taken from people with triple-negative breast cancer. The technology looks at multiple genes at once, looking for mutations that could be linked to breast cancer.
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What is Means to Have a Genetic Predisposition to Cancer

A risk factor is anything that increases your chances of getting a disease, such as breast cancer. But having a risk factor, or even many, does not mean that you are sure to get the disease. Some risk factors for breast cancer are things you cannot change, such as getting older or inheriting certain gene changes. These make your risk of breast cancer higher.
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Two large studies give a much sharper picture of which inherited mutations raise the risk of breast cancer for women without a family history of the disease, and how common these flawed genes are in the general population. Doctors say the results published Wednesday by the New England Journal of Medicine can help women make better decisions about screening, preventive surgery or other steps. King, a University of Washington scientist, had no role in the new studies but discovered the first breast cancer predisposition gene, BRCA1. The American Cancer Society estimates that , new cases of breast cancer were diagnosed in the United States last year.
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